Sunday, October 18, 2009
High O2 and SSIs
In the October 14 JAMA a randomized controlled trial of perioperative hyperoxia failed to show any impact on the incidence of surgical site infection. 1,400 patients were randomized to receive either 80% oxygen or 30% oxygen during laparatomy and for the first two hours post-operatively. Surgical site infections occurred in about 20% of patients in both groups.
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