Originally recovered in 2006 from a Shanghai patient with an intra-abdominal infection, the new Enterococcus faecium was highly resistant to Vancomycin(MIC, >256 µg/ml) and teicoplanin (MIC, 96 µg/ml). The novel vanM cluster shares a similar DNA sequence to vanA, but is arranged more like vanD. At least the VanM, like VanA, confers glycopeptide resistance by the inducible synthesis of precursor ending in D-Ala-D-Lac. One less thing to learn. So now we have to remember vanA, vanB, vanC, vanD, vanE, vanG, vanL and vanM. The enterococcus sure has been busy making new VREs.
November 2010 AAC article Xu X., et al.
Pondering vexing issues in infection prevention and control
Showing posts with label vanM. Show all posts
Showing posts with label vanM. Show all posts
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In many parts of the country, as rates of COVID-19 are declining and vaccination coverage is increasing (albeit with substantial variati...
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I’m surprised that we can’t stop arguing about the modes of SARS-CoV-2 transmission, despite the fact that most experts (including our frie...
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This is a guest post by Jorge Salinas, MD, Hospital Epidemiologist at the University of Iowa Hospitals & Clinics. There is virtually no...