KPC (Yeah You Know Me)
Now that I have your attention, I wanted to point out a recent review in Lancet ID by Silvia Munoz-Price and colleagues. It's behind a paywall with a $31 charge, so hopefully you have access through your institution or can email one of the authors to request a copy. The co-authors do a wonderful job highlighting the emergence of KPC containing strains in the US (1996) and subsequent spread of these β-lactamases throughout the world. Importantly, they discuss treatment options (or lack thereof) and emphasize the important role that infection prevention will play for the foreseeable future. They also suggest that stewardship might be more relevant in plasmid (non-clonal) outbreaks.
The last sentence was a hypothesis of David Livermore, which I think is indeed interesting.
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