The above quote, by Canadian microbiologist Claude Dolman, remains as true today as when he wrote it in 1955. Each time I attend on our busy ID consult service, I’m astonished again at how very nasty, and how very common, is S. aureus. Earlier this week we saw a patient with a confusing clinical presentation (confusing to me, anyway). At the end of the day, as we were going back over plausible etiologies for his symptoms, I said, “it’ll probably end up being just another presentation of invasive S. aureus disease”. As I was saying those words, his admission blood cultures were turning positive for….yes, S. aureus (in this case, methicillin-susceptible S. aureus). At any given time, I’d say about half the patients on our consult service have invasive S. aureus disease (evenly divided between community-acquired and “community-onset healthcare-associated”). If you type “aureus” into the IDWeek online program planner, you’ll get 170 matches. That’s a lot of learnin’ you could do about S. aureus epidemiology, diagnosis, treatment and prevention! So if you haven’t yet signed up, please join us next month in San Diego.